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Formins regulate the Arp2/3-independent polarization of the MTOC to the Immunological Synapse
T cell receptor (TCR)-mediated cytoskeletal reorganization is considered to be Arp2/3-dependent. We therefore examined Arp2/3- and formin-dependent cytoskeletal processes during T cell activation. We demonstrate that without Arp2/3-mediated actin nucleation, stimulated T cells cannot form an F-actin...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836258/ https://ncbi.nlm.nih.gov/pubmed/17306570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.01.008 |
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