Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands

The retinoic acid receptor-related orphan receptors α and γ (RORα (NR1F1) and RORγ (NR1F3)) are orphan nuclear receptors and perform critical roles in regulation of development, metabolism, and immune function. Cholesterol and cholesterol sulfate have been suggested to be RORα ligands, but the physi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wang, Yongjun, Kumar, Naresh, Solt, Laura A., Richardson, Timothy I., Helvering, Leah M., Crumbley, Christine, Garcia-Ordonez, Ruben D., Stayrook, Keith R., Zhang, Xi, Novick, Scott, Chalmers, Michael J., Griffin, Patrick R., Burris, Thomas P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2010
Θέματα:
Gene Regulation
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836105/
https://ncbi.nlm.nih.gov/pubmed/19965867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080614
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