Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands

The retinoic acid receptor-related orphan receptors α and γ (RORα (NR1F1) and RORγ (NR1F3)) are orphan nuclear receptors and perform critical roles in regulation of development, metabolism, and immune function. Cholesterol and cholesterol sulfate have been suggested to be RORα ligands, but the physi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Yongjun, Kumar, Naresh, Solt, Laura A., Richardson, Timothy I., Helvering, Leah M., Crumbley, Christine, Garcia-Ordonez, Ruben D., Stayrook, Keith R., Zhang, Xi, Novick, Scott, Chalmers, Michael J., Griffin, Patrick R., Burris, Thomas P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Gene Regulation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836105/
https://ncbi.nlm.nih.gov/pubmed/19965867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080614
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