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Recruitment of cAMP-response Element-binding Protein and Histone Deacetylase Has Opposite Effects on Glucocorticoid Receptor Gene Transcription
Glucocorticoids control the synthesis of the glucocorticoid receptor (GR) in various tissues through a negative feedback regulation of the mRNA. In this study, we have identified feedback regulatory domains in the human GR gene promoter and examined the roles of GR, the cAMP-response element-binding...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836055/ https://ncbi.nlm.nih.gov/pubmed/20018896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.072728 |
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