Inhibition of protein phosphorylation in MIA pancreatic cancer cells: Confluence of metabolic and signaling pathways

Oxythiamine (OT), a transketolase inhibitor, is known to inhibit pancreatic cancer cell proliferation. In this study, we investigated the effect of inhibition of the transketolase pathway on signaling pathways in MIA PaCa cancer cells using in-house proteomic techniques. We hypothesized that OT alte...

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Bibliografiske detaljer
Main Authors: Zhang, Hengwei, Cao, Rui, Lee, Wai-Nang Paul, Deng, Caishu, Zhao, Yingchun, Lappe, Joan, Recker, Robert, Yen, Yun, Wang, Qi, Tsai, Ming-Ying, Go, Vay Liang, Xiao, Gary Guishan
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836017/
https://ncbi.nlm.nih.gov/pubmed/20035555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr9008805
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