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Nonorthologous replacement of lysyl-tRNA synthetase prevents addition of lysine analogues to the genetic code
Insertion of lysine during protein synthesis depends on the enzyme lysyl-tRNA synthetase (LysRS), which exists in two unrelated forms, LysRS1 and LysRS2. LysRS1 has been found in most archaea and some bacteria, and LysRS2 has been found in eukarya, most bacteria, and a few archaea, but the two prote...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC283595/ https://ncbi.nlm.nih.gov/pubmed/14623972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2036253100 |
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