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Beta-lysine discrimination by lysyl-tRNA synthetase
Elongation factor P is modified with (R)- -lysine by the lysyl-tRNA synthetase (LysRS) paralog PoxA. PoxA specificity is orthogonal to LysRS, despite their high similarity. To investigate - and -lysine recognition by LysRS and PoxA, amino acid replacements were made in the LysRS active site guided b...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196068/ https://ncbi.nlm.nih.gov/pubmed/21925499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.09.008 |
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