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Discrimination of cognate and noncognate substrates at the active site of class I lysyl-tRNA synthetase
The aminoacyl-tRNA synthetases are divided into two unrelated structural classes, with lysyl-tRNA synthetase (LysRS) the only enzyme represented in both classes. Based on the structure of L-lysine complexed with Pyrococcus horikoshii class I LysRS (LysRS1), and homology to glutamyl-tRNA synthetase (...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527480/ https://ncbi.nlm.nih.gov/pubmed/16533047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0523005 |
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