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Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

Apoptosis is a highly regulated form of cell death, characterized by distinctive features such as cellular shrinkage and nuclear condensation. We demonstrate here that proteolytic activation of hPAK65, a p21-activated kinase, induces morphological changes and elicits apoptosis. hPAK65 is cleaved bot...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Ning, MacDonald, Heather, Reinhard, Christoph, Halenbeck, Robert, Roulston, Anne, Shi, Tim, Williams, Lewis T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC28359/
https://ncbi.nlm.nih.gov/pubmed/9391079
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