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Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer

The highly conserved E-type cyclins are core components of the cell cycle machinery, facilitating the transition into S phase through activation of the cyclin dependent kinases, and assembly of pre-replication complexes on DNA. Cyclin E1 and cyclin E2 are assumed to be functionally redundant, as cyc...

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Detalhes bibliográficos
Main Authors: Caldon, C Elizabeth, Musgrove, Elizabeth A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835679/
https://ncbi.nlm.nih.gov/pubmed/20180967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-5-2
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