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Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptases

BACKGROUND: The foamy virus Pol protein is translated independently from Gag using a separate mRNA. Thus, in contrast to orthoretroviruses no Gag-Pol precursor protein is synthesized. Only the integrase domain is cleaved off from Pol resulting in a mature reverse transcriptase harboring the protease...

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Bibliografiske detaljer
Main Authors: Hartl, Maximilian J, Mayr, Florian, Rethwilm, Axel, Wöhrl, Birgitta M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835651/
https://ncbi.nlm.nih.gov/pubmed/20113504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-5
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