Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Developmental Pathway Inhibits Differentiation of Human Glioblastoma Tumor Initiating Cells

Despite similarities between tumor initiating cells with stem-like properties (TICs) and normal neural stem cells, we hypothesized that there may be differences in their differentiation potentials. We now demonstrate that both bone morphogenetic protein (BMP)-mediated and ciliary neurotrophic factor...

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Autores principales: Lee, Jeongwu, Son, Myung Jin, Woolard, Kevin, Donin, Nicholas M., Li, Aiguo, Cheng, Chui H., Kotliarova, Svetlana, Kotliarov, Yuri, Walling, Jennifer, Ahn, Susie, Kim, Misuk, Totonchy, Mariam, Cusack, Thomas, Ene, Chibawanye, Ma, Hilary, Su, Qin, Zenklusen, Jean Claude, Zhang, Wei, Maric, Dragan, Fine, Howard A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835498/
https://ncbi.nlm.nih.gov/pubmed/18167341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.12.005
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