Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Developmental Pathway Inhibits Differentiation of Human Glioblastoma Tumor Initiating Cells

Despite similarities between tumor initiating cells with stem-like properties (TICs) and normal neural stem cells, we hypothesized that there may be differences in their differentiation potentials. We now demonstrate that both bone morphogenetic protein (BMP)-mediated and ciliary neurotrophic factor...

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Hlavní autoři: Lee, Jeongwu, Son, Myung Jin, Woolard, Kevin, Donin, Nicholas M., Li, Aiguo, Cheng, Chui H., Kotliarova, Svetlana, Kotliarov, Yuri, Walling, Jennifer, Ahn, Susie, Kim, Misuk, Totonchy, Mariam, Cusack, Thomas, Ene, Chibawanye, Ma, Hilary, Su, Qin, Zenklusen, Jean Claude, Zhang, Wei, Maric, Dragan, Fine, Howard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835498/
https://ncbi.nlm.nih.gov/pubmed/18167341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.12.005
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