Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Developmental Pathway Inhibits Differentiation of Human Glioblastoma Tumor Initiating Cells

Despite similarities between tumor initiating cells with stem-like properties (TICs) and normal neural stem cells, we hypothesized that there may be differences in their differentiation potentials. We now demonstrate that both bone morphogenetic protein (BMP)-mediated and ciliary neurotrophic factor...

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Detalhes bibliográficos
Main Authors: Lee, Jeongwu, Son, Myung Jin, Woolard, Kevin, Donin, Nicholas M., Li, Aiguo, Cheng, Chui H., Kotliarova, Svetlana, Kotliarov, Yuri, Walling, Jennifer, Ahn, Susie, Kim, Misuk, Totonchy, Mariam, Cusack, Thomas, Ene, Chibawanye, Ma, Hilary, Su, Qin, Zenklusen, Jean Claude, Zhang, Wei, Maric, Dragan, Fine, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835498/
https://ncbi.nlm.nih.gov/pubmed/18167341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.12.005
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