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Epigenetic Silencing of MicroRNA miR-107 Regulates Cyclin-Dependent Kinase 6 Expression in Pancreatic Cancer

Aberrant expression of microRNAs (miRNAs) has emerged as an important hallmark of cancer. However, the putative mechanisms regulating miRNAs per se are only partially known. It is well established that many tumor suppressor genes in human cancers are silenced by chromatin alterations, including prom...

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Bibliografische gegevens
Hoofdauteurs: Lee, Kwang-Hyuck, Lotterman, Craig, Karikari, Collins, Omura, Noriyuki, Feldmann, Georg, Habbe, Nils, Goggins, Michael G., Mendell, Joshua T., Maitra, Anirban
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger AG 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835374/
https://ncbi.nlm.nih.gov/pubmed/19407485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000186051
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