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Epigenetic Silencing of MicroRNA miR-107 Regulates Cyclin-Dependent Kinase 6 Expression in Pancreatic Cancer

Aberrant expression of microRNAs (miRNAs) has emerged as an important hallmark of cancer. However, the putative mechanisms regulating miRNAs per se are only partially known. It is well established that many tumor suppressor genes in human cancers are silenced by chromatin alterations, including prom...

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Main Authors: Lee, Kwang-Hyuck, Lotterman, Craig, Karikari, Collins, Omura, Noriyuki, Feldmann, Georg, Habbe, Nils, Goggins, Michael G., Mendell, Joshua T., Maitra, Anirban
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835374/
https://ncbi.nlm.nih.gov/pubmed/19407485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000186051
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