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Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth

To identify potentially important genes dysregulated in pancreatic cancer, we analyzed genome-wide transcriptional analysis of pancreatic cancers and normal pancreatic duct samples and identified the transcriptional coactivator, EYA2 (Drosophila Eyes Absent Homologue-2) as silenced in the majority o...

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Detalhes bibliográficos
Main Authors: Vincent, Audrey, Hong, Seung-Mo, Hu, Chaoxin, Omura, Noriyuki, Young, Angela, Kim, Haeryoung, Yu, Jun, Knight, Spencer, Ayars, Michael, Griffith, Margaret, Van Seuningen, Isabelle, Maitra, Anirban, Goggins, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058028/
https://ncbi.nlm.nih.gov/pubmed/24810906
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