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New Insights on Adenovirus as Vaccine Vectors
Adenovirus (Ad) vectors were initially developed for treatment of genetic diseases. Their usefulness for permanent gene replacement was limited by their high immunogenicity, which resulted in rapid elimination of transduced cells through induction of T and B cells to antigens of Ad and the transgene...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835230/ https://ncbi.nlm.nih.gov/pubmed/19513019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.130 |
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