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New Insights on Adenovirus as Vaccine Vectors

Adenovirus (Ad) vectors were initially developed for treatment of genetic diseases. Their usefulness for permanent gene replacement was limited by their high immunogenicity, which resulted in rapid elimination of transduced cells through induction of T and B cells to antigens of Ad and the transgene...

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Autors principals: Lasaro, Marcio O, Ertl, Hildegund CJ
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835230/
https://ncbi.nlm.nih.gov/pubmed/19513019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.130
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