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New Insights on Adenovirus as Vaccine Vectors
Adenovirus (Ad) vectors were initially developed for treatment of genetic diseases. Their usefulness for permanent gene replacement was limited by their high immunogenicity, which resulted in rapid elimination of transduced cells through induction of T and B cells to antigens of Ad and the transgene...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835230/ https://ncbi.nlm.nih.gov/pubmed/19513019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.130 |
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