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New Insights on Adenovirus as Vaccine Vectors

Adenovirus (Ad) vectors were initially developed for treatment of genetic diseases. Their usefulness for permanent gene replacement was limited by their high immunogenicity, which resulted in rapid elimination of transduced cells through induction of T and B cells to antigens of Ad and the transgene...

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מידע ביבליוגרפי
Main Authors: Lasaro, Marcio O, Ertl, Hildegund CJ
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835230/
https://ncbi.nlm.nih.gov/pubmed/19513019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.130
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