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Association of the Mediator complex with enhancers of active genes

The multiprotein Mediator complex has been shown to interact with gene-specific regulatory proteins and RNA polymerase II in vitro. Here, we use chromatin immunoprecipitation to analyze the recruitment of Mediator to GAL genes of yeast in vivo. We find that Mediator associates exclusively with trans...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kuras, Laurent, Borggrefe, Tilman, Kornberg, Roger D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283516/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14623974/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2036346100
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