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An infectious arterivirus cDNA clone: Identification of a replicase point mutation that abolishes discontinuous mRNA transcription

Equine arteritis virus (EAV) is a positive-strand RNA virus that uses a discontinuous transcription mechanism to generate a nested set of six subgenomic mRNAs from which its structural genes are expressed. A stable bacterial plasmid (pEAV030) containing a full-length cDNA copy of the 12.7-kb EAV gen...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: van Dinten, Leonie C., den Boon, Johan A., Wassenaar, Alfred L. M., Spaan, Willy J. M., Snijder, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19627/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023370/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.3.991
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