Processing of the equine arteritis virus replicase ORF1b protein: identification of cleavage products containing the putative viral polymerase and helicase domains.

The replicase open reading frame lb (ORF1b) protein of equine arteritis virus (EAV) is expressed from the viral genome as an ORF1ab fusion protein (345 kDa) by ribosomal frameshifting. Processing of the ORF1b polyprotein was predicted to be mediated by the nsp4 serine protease, the main EAV protease...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	van Dinten, L C, Wassenaar, A L, Gorbalenya, A E, Spaan, W J, Snijder, E J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8794297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.10.6625-6633.1996
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