A Novel Estrogen Receptor Intramolecular Folding–based Titratable Transgene Expression System

The use of regulated gene expression systems is important for successful gene therapy applications. In this study, ligand-induced structural change in the estrogen receptor (ER) was used to develop a novel ER intramolecular folding–based transcriptional activation system. The system was studied usin...

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Main Authors: Paulmurugan, Ramasamy, Padmanabhan, Parasuraman, Ahn, Byeong-Cheol, Ray, Sunetra, Willmann, Juergen K, Massoud, Tarik F, Biswal, Sandip, Gambhir, Sanjiv S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835012/
https://ncbi.nlm.nih.gov/pubmed/19654568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.171
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