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A Novel Estrogen Receptor Intramolecular Folding–based Titratable Transgene Expression System
The use of regulated gene expression systems is important for successful gene therapy applications. In this study, ligand-induced structural change in the estrogen receptor (ER) was used to develop a novel ER intramolecular folding–based transcriptional activation system. The system was studied usin...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835012/ https://ncbi.nlm.nih.gov/pubmed/19654568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.171 |
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