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A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography
Improved techniques to non-invasively image protein-protein interactions (PPIs) are essential. We molecularly engineered a positron emission tomography (PET)-based split reporter (herpes simplex virus type 1 thymidine kinase [TK]), split between Thr265 and Ala266, and used this in a protein-fragment...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917476/ https://ncbi.nlm.nih.gov/pubmed/20639890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2185 |
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