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A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography

Improved techniques to non-invasively image protein-protein interactions (PPIs) are essential. We molecularly engineered a positron emission tomography (PET)-based split reporter (herpes simplex virus type 1 thymidine kinase [TK]), split between Thr265 and Ala266, and used this in a protein-fragment...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Massoud, Tarik F., Paulmurugan, Ramasamy, Gambhir, Sanjiv S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917476/
https://ncbi.nlm.nih.gov/pubmed/20639890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2185
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