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Conversion of the allosteric transition of GroEL from concerted to sequential by the single mutation Asp-155 → Ala
The reaction cycle of the double-ring chaperonin GroEL is driven by ATP binding that takes place with positive cooperativity within each seven-membered ring and negative cooperativity between rings. The positive cooperativity within rings is due to ATP binding-induced conformational changes that are...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC283501/ https://ncbi.nlm.nih.gov/pubmed/14615587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2333925100 |
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