GSK3β Promotes Apoptosis after Renal Ischemic Injury

The mechanism by which the serine-threonine kinase glycogen synthase kinase-3β (GSK3β) affects survival of renal epithelial cells after acute stress is unknown. Using in vitro and in vivo models, we tested the hypothesis that GSK3β promotes Bax-mediated apoptosis, contributing to tubular injury and...

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Detalhes bibliográficos
Main Authors: Wang, Zhiyong, Havasi, Andrea, Gall, Jonathan, Bonegio, Ramon, Li, Zhijian, Mao, Haiping, Schwartz, John H., Borkan, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834548/
https://ncbi.nlm.nih.gov/pubmed/20093356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009080828
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