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The bHLH/PAS transcription factor singleminded 2s promotes mammary gland lactogenic differentiation

We have previously demonstrated that the bHLH/PAS transcription factor, singleminded 2s (Sim2s), is required for proper mammary ductal morphogenesis and luminal epithelial differentiation. Furthermore, loss of Sim2s in breast cancer cells resulted in downregulation of epithelial markers and acquisit...

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Hlavní autoři: Wellberg, Elizabeth, Metz, Richard P., Parker, Caitlin, Porter, Weston W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834457/
https://ncbi.nlm.nih.gov/pubmed/20150276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.041657
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