The bHLH/PAS transcription factor singleminded 2s promotes mammary gland lactogenic differentiation

We have previously demonstrated that the bHLH/PAS transcription factor, singleminded 2s (Sim2s), is required for proper mammary ductal morphogenesis and luminal epithelial differentiation. Furthermore, loss of Sim2s in breast cancer cells resulted in downregulation of epithelial markers and acquisit...

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Bibliografiske detaljer
Main Authors: Wellberg, Elizabeth, Metz, Richard P., Parker, Caitlin, Porter, Weston W.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2010
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834457/
https://ncbi.nlm.nih.gov/pubmed/20150276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.041657
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