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Structural characterization of mammalian bHLH-PAS transcription factors

The mammalian basic helix-loop-helix-PER-ARNT-SIM (bHLH–PAS) transcription factors share common architectural features that include a bHLH DNA-binding domain and tandemly positioned PAS domains. The sixteen members of this family include the hypoxia-inducible factors (HIF-1α and HIF-2α), ARNT (also...

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書目詳細資料
發表在:Curr Opin Struct Biol
Main Authors: Wu, Dalei, Rastinejad, Fraydoon
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382129/
https://ncbi.nlm.nih.gov/pubmed/27721191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.09.011
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