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Structural characterization of mammalian bHLH-PAS transcription factors

The mammalian basic helix-loop-helix-PER-ARNT-SIM (bHLH–PAS) transcription factors share common architectural features that include a bHLH DNA-binding domain and tandemly positioned PAS domains. The sixteen members of this family include the hypoxia-inducible factors (HIF-1α and HIF-2α), ARNT (also...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Wu, Dalei, Rastinejad, Fraydoon
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382129/
https://ncbi.nlm.nih.gov/pubmed/27721191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.09.011
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