Agonist-dependent μ-opioid receptor signaling can lead to heterologous desensitization

Desensitization of the μ-opioid receptor (MOR) has been implicated as an important regulatory process in the development of tolerance to opiates. Monitoring the release of intracellular Ca(2+) ([Ca(2+)](i)), we reported that [D-Ala(2), N-Me-Phe(4), Gly(5)-ol]-enkephalin (DAMGO)-induced receptor dese...

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Bibliografiska uppgifter
Huvudupphovsmän: Chu, Ji, Zheng, Hui, Zhang, Yuhan, Loh, Horace H., Law, Ping-Yee
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833358/
https://ncbi.nlm.nih.gov/pubmed/20043990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.12.003
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