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Agonist-dependent μ-opioid receptor signaling can lead to heterologous desensitization
Desensitization of the μ-opioid receptor (MOR) has been implicated as an important regulatory process in the development of tolerance to opiates. Monitoring the release of intracellular Ca(2+) ([Ca(2+)](i)), we reported that [D-Ala(2), N-Me-Phe(4), Gly(5)-ol]-enkephalin (DAMGO)-induced receptor dese...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833358/ https://ncbi.nlm.nih.gov/pubmed/20043990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.12.003 |
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