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β-Arrestin-Dependent μ-Opioid Receptor-Activated Extracellular Signal-Regulated Kinases (ERKs) Translocate to Nucleus in Contrast to G Protein-Dependent ERK Activation

The cellular location of extracellular signal-regulated kinases (ERKs) activated by a G protein-coupled receptor was shown to be dependent on the pathway that mediated their activation. In general, fast activation of ERKs (2 min) mediated by G proteins resulted in the nuclear translocation of phosph...

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Detalhes bibliográficos
Main Authors: Zheng, Hui, Loh, Horace H., Law, Ping-Yee
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253657/
https://ncbi.nlm.nih.gov/pubmed/17947509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.039842
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