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Involvement of Phosphoinositide 3-Kinase γ in Angiogenesis and Healing of Experimental Myocardial Infarction in Mice

RATIONALE: Phosphoinositide 3-kinase (PI3K)γ is expressed in hematopoietic cells, endothelial cells (ECs), and cardiomyocytes and regulates different cellular functions relevant to inflammation, tissue remodeling and cicatrization. Recently, PI3Kγ inhibitors have been indicated for the treatment of...

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Bibliografiske detaljer
Main Authors: Siragusa, Mauro, Katare, Rajesh, Meloni, Marco, Damilano, Federico, Hirsch, Emilio, Emanueli, Costanza, Madeddu, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833289/
https://ncbi.nlm.nih.gov/pubmed/20056919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.207449
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