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Benfotiamine improves functional recovery of the infarcted heart via activation of pro-survival G6PD/Akt signaling pathway and modulation of neurohormonal response

Benfotiamine (BFT) is a transketolase activator that directs glucose to the pentose phosphate pathway. The present study investigated whether BFT improves the recovery after myocardial infarction (MI) and explored underlying mechanisms of protection. Non-diabetic and streptozotocin-induced type 1 di...

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Autors principals: Katare, Rajesh, Caporali, Andrea, Emanueli, Costanza, Madeddu, Paolo
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017952/
https://ncbi.nlm.nih.gov/pubmed/20542491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.05.014
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