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Biodegradable Calcium Phosphate Nanoparticle with Lipid Coating for Systemic siRNA Delivery
A lipid coated calcium phosphate (LCP) nanoparticle (NP) formulation was developed for efficient delivery of small interfering RNA (siRNA) to a xenograft tumor model by intravenous administration. Based on the previous formulation, liposome-polycation-DNA (LPD), which was DNA-protamine complex wrapp...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833237/ https://ncbi.nlm.nih.gov/pubmed/19919845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.11.008 |
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