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Calcium phosphate nanoparticles-based systems for siRNA delivery

Despite the enormous therapeutic potential of siRNA as a treatment strategy, the delivery is still a problem due to unfavorable biodistribution profiles and poor intracellular bioavailability. Calcium phosphate (CaP) co-precipitate has been used for nearly 40 years for in vitro transfection due to i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Regen Biomater
Hauptverfasser: Xu, Xiaochun, Li, Zehao, Zhao, Xueqin, Keen, Lawrence, Kong, Xiangdong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881614/
https://ncbi.nlm.nih.gov/pubmed/27252888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rb/rbw010
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