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Proteasome Assembly Influences Interaction with Ubiquitinated Proteins and Shuttle Factors
A major fraction of intracellular protein degradation is mediated by the proteasome. Successful degradation of these substrates requires ubiquitination and delivery to the proteasome followed by protein unfolding and disassembly of the multiubiquitin chain. Enzymes, such as Rpn11, dismantle multiubi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832983/ https://ncbi.nlm.nih.gov/pubmed/20061387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.076786 |
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