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Proteasome Assembly Influences Interaction with Ubiquitinated Proteins and Shuttle Factors

A major fraction of intracellular protein degradation is mediated by the proteasome. Successful degradation of these substrates requires ubiquitination and delivery to the proteasome followed by protein unfolding and disassembly of the multiubiquitin chain. Enzymes, such as Rpn11, dismantle multiubi...

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Detalhes bibliográficos
Main Authors: Chandra, Abhishek, Chen, Li, Liang, Huiyan, Madura, Kiran
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832983/
https://ncbi.nlm.nih.gov/pubmed/20061387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.076786
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