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p62 Serves as a Shuttling Factor for TrkA Interaction with the Proteasome
The scaffold protein p62 is involved in internalization and trafficking of TrkA. The receptor is deubiquitinated by the proteasomes prior to degradation by lysosomes. Here we demonstrate that p62 serves as a shuttling protein for interaction of ubiquitinated TrkA with Rpt1, one of the six ATPases of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561188/ https://ncbi.nlm.nih.gov/pubmed/18598672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.06.082 |
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