Characterization of a Novel Class of Polyphenolic Inhibitors of Plasminogen Activator Inhibitor-1

Plasminogen activator inhibitor type 1, (PAI-1) the primary inhibitor of the tissue-type (tPA) and urokinase-type (uPA) plasminogen activators, has been implicated in a wide range of pathological processes, making it an attractive target for pharmacologic inhibition. Currently available small-molecu...

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Detalhes bibliográficos
Main Authors: Cale, Jacqueline M., Li, Shih-Hon, Warnock, Mark, Su, Enming J., North, Paul R., Sanders, Karen L., Puscau, Maria M., Emal, Cory D., Lawrence, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832939/
https://ncbi.nlm.nih.gov/pubmed/20061381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.067967
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