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The Loop Connecting Metal-Binding Domains 3 and 4 of ATP7B Is a Target of a Kinase-Mediated Phosphorylation

Cu-ATPase ATP7B (Wilson’s disease protein) transports copper into the trans-Golgi network for biosynthetic incorporation into ceruloplasmin and sequesters excess copper to endocytic vesicles for further export out of the cell. The activity and intracellular location of ATP7B are regulated by copper...

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Autors principals: Bartee, Mee Y., Ralle, Martina, Lutsenko, Svetlana
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832749/
https://ncbi.nlm.nih.gov/pubmed/19405516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900325k
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