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Interactions between Metal-binding Domains Modulate Intracellular Targeting of Cu(I)-ATPase ATP7B, as Revealed by Nanobody Binding

The biologically and clinically important membrane transporters are challenging proteins to study because of their low level of expression, multidomain structure, and complex molecular dynamics that underlies their activity. ATP7B is a copper transporter that traffics between the intracellular compa...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Huang, Yiping, Nokhrin, Sergiy, Hassanzadeh-Ghassabeh, Gholamreza, Yu, Corey H., Yang, Haojun, Barry, Amanda N., Tonelli, Marco, Markley, John L., Muyldermans, Serge, Dmitriev, Oleg Y., Lutsenko, Svetlana
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239620/
https://ncbi.nlm.nih.gov/pubmed/25253690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.580845
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