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Interactions between Metal-binding Domains Modulate Intracellular Targeting of Cu(I)-ATPase ATP7B, as Revealed by Nanobody Binding

The biologically and clinically important membrane transporters are challenging proteins to study because of their low level of expression, multidomain structure, and complex molecular dynamics that underlies their activity. ATP7B is a copper transporter that traffics between the intracellular compa...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Huang, Yiping, Nokhrin, Sergiy, Hassanzadeh-Ghassabeh, Gholamreza, Yu, Corey H., Yang, Haojun, Barry, Amanda N., Tonelli, Marco, Markley, John L., Muyldermans, Serge, Dmitriev, Oleg Y., Lutsenko, Svetlana
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239620/
https://ncbi.nlm.nih.gov/pubmed/25253690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.580845
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