Designing Focused Chemical Libraries Enriched in Protein-Protein Interaction Inhibitors using Machine-Learning Methods

Protein-protein interactions (PPIs) may represent one of the next major classes of therapeutic targets. So far, only a minute fraction of the estimated 650,000 PPIs that comprise the human interactome are known with a tiny number of complexes being drugged. Such intricate biological systems cannot b...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Reynès, Christelle, Host, Hélène, Camproux, Anne-Claude, Laconde, Guillaume, Leroux, Florence, Mazars, Anne, Deprez, Benoit, Fahraeus, Robin, Villoutreix, Bruno O., Sperandio, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832677/
https://ncbi.nlm.nih.gov/pubmed/20221258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000695
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker