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A leap into the chemical space of protein-protein interaction inhibitors

Protein-protein interactions (PPI) are involved in vital cellular processes and are therefore associated to a growing number of diseases. But working with them as therapeutic targets comes with some major hurdles that require substantial mutations from our way to design to drugs on historical target...

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Detalhes bibliográficos
Main Authors: Villoutreix, Bruno O., Labbé, Céline, Lagorce, David, Laconde, Guillaume, Sperandio, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901718/
https://ncbi.nlm.nih.gov/pubmed/22650260
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