Drug-Like Protein–Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology

Fundamental processes in living cells are largely controlled by macromolecular interactions and among them, protein–protein interactions (PPIs) have a critical role while their dysregulations can contribute to the pathogenesis of numerous diseases. Although PPIs were considered as attractive pharmac...

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Autors principals: Villoutreix, Bruno O, Kuenemann, Melaine A, Poyet, Jean-Luc, Bruzzoni-Giovanelli, Heriberto, Labbé, Céline, Lagorce, David, Sperandio, Olivier, Miteva, Maria A
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2014
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160817/
https://ncbi.nlm.nih.gov/pubmed/25254076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201400040
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