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Probing the effect of amino-terminal truncation for Aβ(1–40) peptides
We examine the effect of deletion of the amino-terminal (residues 1 to 9) on the structure and energetics of Aβ(1–40) peptides. To this end, we use replica exchange molecular dynamics to compare the conformational ensembles of Aβ(1–40) and amino-truncated Aβ(10–40) monomers and dimers. Overall, the...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832594/ https://ncbi.nlm.nih.gov/pubmed/19419218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp9016773 |
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