The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signalling

Chemoresistance represents a major problem in the treatment of many malignancies. Overcoming this obstacle will require improved understanding of the mechanisms responsible for the phenomenon. The progenitor cell marker NG2/MPG is aberrantly expressed by various tumors, but its role in cell death si...

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Hauptverfasser: Chekenya, M, Krakstad, C, Svendsen, A, Netland, IA, Staalesen, V, Tysnes, B.B, Selheim, F, Wang, J, Sakariassen, P.Ø, Sandal, T, Lønning, P.E, Flatmark, T, Enger, P.Ø, Bjerkvig, R, Sioud, M, Stallcup, WB
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832310/
https://ncbi.nlm.nih.gov/pubmed/18469852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.157
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