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Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma

Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are not completely understood. However, cancer cells with an immature stem-like phenotype are hypothesised to play a role in r...

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Hlavní autoři: Svendsen, Agnete, Verhoeff, Joost J. C., Immervoll, Heike, Brøgger, Jan C., Kmiecik, Justyna, Poli, Aurelie, Netland, Inger A., Prestegarden, Lars, Planagumà, Jesús, Torsvik, Anja, Kjersem, Anneli Bohne, Sakariassen, Per Ø., Heggdal, Jan I., Van Furth, Wouter R., Bjerkvig, Rolf, Lund-Johansen, Morten, Enger, Per Ø., Felsberg, Joerg, Brons, Nicolaas H. C., Tronstad, Karl J., Waha, Andreas, Chekenya, Martha
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185228/
https://ncbi.nlm.nih.gov/pubmed/21863242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0867-2
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