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Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma

Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are not completely understood. However, cancer cells with an immature stem-like phenotype are hypothesised to play a role in r...

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Bibliografski detalji
Glavni autori: Svendsen, Agnete, Verhoeff, Joost J. C., Immervoll, Heike, Brøgger, Jan C., Kmiecik, Justyna, Poli, Aurelie, Netland, Inger A., Prestegarden, Lars, Planagumà, Jesús, Torsvik, Anja, Kjersem, Anneli Bohne, Sakariassen, Per Ø., Heggdal, Jan I., Van Furth, Wouter R., Bjerkvig, Rolf, Lund-Johansen, Morten, Enger, Per Ø., Felsberg, Joerg, Brons, Nicolaas H. C., Tronstad, Karl J., Waha, Andreas, Chekenya, Martha
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185228/
https://ncbi.nlm.nih.gov/pubmed/21863242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0867-2
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